Clinical Studies for People Either With or Without Diabetes

TINSAL-CVD

Seeking volunteers, ages 21-70 who have heart disease and are overweight for a research study that is comparing standard care for heart disease with either individualized exercise and weight-loss program or an investigational medication.

The study medication has been approved by the U.S. Food and Drug Administration (FDA) to treat arthritis but has not been approved for heart disease. Study involves 10-11 visits to Boston's Beth Israel Deaconess Medical Center or Joslin Diabetes Center over about 32 months.

Eligible participants will either get lifestyle education and nutritional/medical supplements or take the investigational medication or placebo (pill with no active medication). Compensation available.

Call: 1-617-264-2727 or 1-866-622-3884 toll free or email: TINSAL-CVD@joslin.harvard.edu

(CHS#06-13)

Description: The SUGAR MGH Research Study will evaluate whether the different genes people inherit change the response to medications that are commonly used to treat type 2 diabetes, metformin and glipizide.  As part of the study participants will be asked to take these medications and will also be given a sugar drink. 

The study involves two visits to the Joslin Diabetes Clinic one week apart, the first visit takes about 5 hours and the second about 3 hours.  Blood will be drawn at both visits.  Participants will receive monetary compensation, a parking voucher and a free meal for each completed visit. 

Recruiting: We are seeking research volunteers over the age of 18 years who have diabetes but are not currently on diabetes medication, and/or who may be at risk for diabetes (for example, risk factors include high or “borderline-high” blood sugars, being overweight, having a history of gestational diabetes (diabetes during pregnancy), being an ethnic minority, or having a first degree relative with type 2 diabetes). 

Contact: Laurel Garber laurel.garber@joslin.harvard.edu 617-309-4478